AMP-activated protein kinase alpha1 promotes tumor development via FOXP3 elevation in tumor-infiltrating Treg cells

Overwhelming evidence indicates that infiltration of tumors by Treg cells with elevated levels of FOXP3 suppresses the host antitumor immune response. However, the molecular mechanisms that maintain high expression of FOXP3 in tumor-infiltrating Treg cells remain elusive. Here, we report that AMP-ac...

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Detalles Bibliográficos
Autores principales: An, Junqing, Ding, Ye, Yu, Changjiang, Li, Jian, You, Shaojin, Liu, Zhixue, Song, Ping, Zou, Ming-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704466/
https://www.ncbi.nlm.nih.gov/pubmed/34988407
http://dx.doi.org/10.1016/j.isci.2021.103570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704466/
https://www.ncbi.nlm.nih.gov/pubmed/34988407
http://dx.doi.org/10.1016/j.isci.2021.103570

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