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AMP-activated protein kinase alpha1 promotes tumor development via FOXP3 elevation in tumor-infiltrating Treg cells
Overwhelming evidence indicates that infiltration of tumors by Treg cells with elevated levels of FOXP3 suppresses the host antitumor immune response. However, the molecular mechanisms that maintain high expression of FOXP3 in tumor-infiltrating Treg cells remain elusive. Here, we report that AMP-ac...
Autores principales: | An, Junqing, Ding, Ye, Yu, Changjiang, Li, Jian, You, Shaojin, Liu, Zhixue, Song, Ping, Zou, Ming-Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704466/ https://www.ncbi.nlm.nih.gov/pubmed/34988407 http://dx.doi.org/10.1016/j.isci.2021.103570 |
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