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Evolutionary modeling reveals enhanced mutational flexibility of HCV subtype 1b compared with 1a

Hepatitis C virus (HCV) is a leading cause of liver-associated disease and liver cancer. Of the major HCV subtypes, patients infected with subtype 1b have been associated with having a higher risk of developing chronic infection and hepatocellular carcinoma. However, underlying reasons for this incr...

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Detalles Bibliográficos
Autores principales: Zhang, Hang, Quadeer, Ahmed A., McKay, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704487/
https://www.ncbi.nlm.nih.gov/pubmed/34988406
http://dx.doi.org/10.1016/j.isci.2021.103569