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Evolutionary modeling reveals enhanced mutational flexibility of HCV subtype 1b compared with 1a
Hepatitis C virus (HCV) is a leading cause of liver-associated disease and liver cancer. Of the major HCV subtypes, patients infected with subtype 1b have been associated with having a higher risk of developing chronic infection and hepatocellular carcinoma. However, underlying reasons for this incr...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704487/ https://www.ncbi.nlm.nih.gov/pubmed/34988406 http://dx.doi.org/10.1016/j.isci.2021.103569 |