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Amino acid primed mTOR activity is essential for heart regeneration
Heart disease is the leading cause of death with no method to repair damaged myocardium due to the limited proliferative capacity of adult cardiomyocytes. Curiously, mouse neonates and zebrafish can regenerate their hearts via cardiomyocyte de-differentiation and proliferation. However, a molecular...
Autores principales: | Miklas, Jason W., Levy, Shiri, Hofsteen, Peter, Mex, Diego Ic, Clark, Elisa, Muster, Jeanot, Robitaille, Aaron M., Sivaram, Gargi, Abell, Lauren, Goodson, Jamie M., Pranoto, Inez, Madan, Anup, Chin, Michael T., Tian, Rong, Murry, Charles E., Moon, Randall T., Wang, Yuliang, Ruohola-Baker, Hannele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704488/ https://www.ncbi.nlm.nih.gov/pubmed/34988408 http://dx.doi.org/10.1016/j.isci.2021.103574 |
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