Cyclodextrin Complexed Lipid Nanoparticles of Irbesartan for Oral Applications: Design, Development, and In Vitro Characterization

Irbesartan (IR) is an angiotensin II receptor antagonist drug with antihypertensive activity. IR bioavailability is limited due to poor solubility and first-pass metabolism. The current investigation aimed to design, develop, and characterize the cyclodextrin(s) (CD) complexed IR (IR-CD) loaded soli...

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Detalles Bibliográficos
Autores principales: Dudhipala, Narendar, Ettireddy, Swetha, Youssef, Ahmed Adel Ali, Puchchakayala, Goverdhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704533/
https://www.ncbi.nlm.nih.gov/pubmed/34946619
http://dx.doi.org/10.3390/molecules26247538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704533/
https://www.ncbi.nlm.nih.gov/pubmed/34946619
http://dx.doi.org/10.3390/molecules26247538

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