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Cyclodextrin Complexed Lipid Nanoparticles of Irbesartan for Oral Applications: Design, Development, and In Vitro Characterization
Irbesartan (IR) is an angiotensin II receptor antagonist drug with antihypertensive activity. IR bioavailability is limited due to poor solubility and first-pass metabolism. The current investigation aimed to design, develop, and characterize the cyclodextrin(s) (CD) complexed IR (IR-CD) loaded soli...
Autores principales: | Dudhipala, Narendar, Ettireddy, Swetha, Youssef, Ahmed Adel Ali, Puchchakayala, Goverdhan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704533/ https://www.ncbi.nlm.nih.gov/pubmed/34946619 http://dx.doi.org/10.3390/molecules26247538 |
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