Propagation of SARS-CoV-2 in Calu-3 Cells to Eliminate Mutations in the Furin Cleavage Site of Spike

SARS-CoV-2 pathogenesis, vaccine, and therapeutic studies rely on the use of animals challenged with highly pathogenic virus stocks produced in cell cultures. Ideally, these virus stocks should be genetically and functionally similar to the original clinical isolate, retaining wild-type properties t...

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Detalles Bibliográficos
Autores principales: Baczenas, John James, Andersen, Hanne, Rashid, Sujatha, Yarmosh, David, Puthuveetil, Nikhita, Parker, Michael, Bradford, Rebecca, Florence, Clint, Stemple, Kimberly J., Lewis, Mark G., O’Connor, Shelby L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704555/
https://www.ncbi.nlm.nih.gov/pubmed/34960703
http://dx.doi.org/10.3390/v13122434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704555/
https://www.ncbi.nlm.nih.gov/pubmed/34960703
http://dx.doi.org/10.3390/v13122434

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