The Artemiside-Artemisox-Artemisone-M1 Tetrad: Efficacies against Blood Stage P. falciparum Parasites, DMPK Properties, and the Case for Artemiside

Because of the need to replace the current clinical artemisinins in artemisinin combination therapies, we are evaluating fitness of amino-artemisinins for this purpose. These include the thiomorpholine derivative artemiside obtained in one scalable synthetic step from dihydroartemisinin (DHA) and th...

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Detalles Bibliográficos
Autores principales: Gibhard, Liezl, Coertzen, Dina, Reader, Janette, van der Watt, Mariëtte E., Birkholtz, Lyn-Marie, Wong, Ho Ning, Batty, Kevin T., Haynes, Richard K., Wiesner, Lubbe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704606/
https://www.ncbi.nlm.nih.gov/pubmed/34959347
http://dx.doi.org/10.3390/pharmaceutics13122066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704606/
https://www.ncbi.nlm.nih.gov/pubmed/34959347
http://dx.doi.org/10.3390/pharmaceutics13122066

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