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Compound screen identifies the small molecule Q34 as an inhibitor of SARS-CoV-2 infection

The COVID-19 outbreak poses a serious threat to global public health. Effective countermeasures and approved therapeutics are desperately needed. In this study, we screened a small molecule library containing the NCI-DTP compounds to identify molecules that can prevent SARS-CoV-2 cellular entry. By...

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Detalles Bibliográficos
Autores principales: Cui, Qi, Garcia, Gustavo, Zhang, Mingzi, Wang, Cheng, Li, Hongzhi, Zhou, Tao, Sun, Guihua, Arumugaswami, Vaithilingaraja, Shi, Yanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704726/
https://www.ncbi.nlm.nih.gov/pubmed/34977495
http://dx.doi.org/10.1016/j.isci.2021.103684