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The Very First Modification of Pleuromutilin and Lefamulin by Photoinitiated Radical Addition Reactions—Synthesis and Antibacterial Studies

Pleuromutilin is a fungal diterpene natural product with antimicrobial properties, semisynthetic derivatives of which are used in veterinary and human medicine. The development of bacterial resistance to pleuromutilins is known to be very slow, which makes the tricyclic diterpene skeleton of pleurom...

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Detalles Bibliográficos
Autores principales: Thai Le, Son, Páll, Dávid, Rőth, Erzsébet, Tran, Tuyen, Debreczeni, Nóra, Bege, Miklós, Bereczki, Ilona, Ostorházi, Eszter, Milánkovits, Márton, Herczegh, Pál, Borbás, Anikó, Csávás, Magdolna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704873/
https://www.ncbi.nlm.nih.gov/pubmed/34959310
http://dx.doi.org/10.3390/pharmaceutics13122028