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Inactivated SARS-CoV-2 induces acute respiratory distress syndrome in human ACE2-transgenic mice

The development of animal models for COVID-19 is essential for basic research and drug/vaccine screening. Previously reported COVID-19 animal models need to be established under a high biosafety level condition for the utilization of live SARS-CoV-2, which greatly limits its application in routine r...

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Detalles Bibliográficos
Autores principales: Bi, Zhenfei, Hong, Weiqi, Que, Haiying, He, Cai, Ren, Wenyan, Yang, Jingyun, Lu, Tianqi, Chen, Li, Lu, Shuaiyao, Peng, Xiaozhong, Wei, Xiawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705082/
https://www.ncbi.nlm.nih.gov/pubmed/34952899
http://dx.doi.org/10.1038/s41392-021-00851-6