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Lupinus albus Protein Components Inhibit MMP-2 and MMP-9 Gelatinolytic Activity In Vitro and In Vivo

Matrix metalloproteinases 2 and 9 (MMP-2 and MMP-9) are regarded as important clinical targets due to their nodal-point role in inflammatory and oncological diseases. Here, we aimed at isolating and characterizing am MMP-2 and-9 inhibitor (MMPI) from Lupinus albus and at assessing its efficacy in vi...

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Detalles Bibliográficos
Autores principales: Mota, Joana, Direito, Rosa, Rocha, João, Fernandes, João, Sepodes, Bruno, Figueira, Maria Eduardo, Raymundo, Anabela, Lima, Ana, Ferreira, Ricardo Boavida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705115/
https://www.ncbi.nlm.nih.gov/pubmed/34948082
http://dx.doi.org/10.3390/ijms222413286