IRF4 expression is low in Philadelphia negative myeloproliferative neoplasms and is associated with a worse prognosis

Interferon regulatory factor 4 (IRF4) is involved in the pathogenesis of various hematologic malignancies. Its expression has been related to the negative regulation of myeloid-derived suppressor cells (MDSCs) and the polarization of anti-inflammatory M2 macrophages, thereby altering immunosurveilla...

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Detalles Bibliográficos
Autores principales: Cumbo, Cosimo, Tarantini, Francesco, Anelli, Luisa, Zagaria, Antonella, Redavid, Immacolata, Minervini, Crescenzio Francesco, Coccaro, Nicoletta, Tota, Giuseppina, Ricco, Alessandra, Parciante, Elisa, Conserva, Maria Rosa, Specchia, Giorgina, Musto, Pellegrino, Albano, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705160/
https://www.ncbi.nlm.nih.gov/pubmed/34952638
http://dx.doi.org/10.1186/s40164-021-00253-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705160/
https://www.ncbi.nlm.nih.gov/pubmed/34952638
http://dx.doi.org/10.1186/s40164-021-00253-y

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