Production of 9,21-dihydroxy-20-methyl-pregna-4-en-3-one from phytosterols in Mycobacterium neoaurum by modifying multiple genes and improving the intracellular environment

BACKGROUND: Steroid drugs are essential for disease prevention and clinical treatment. However, due to intricated steroid structure, traditional chemical methods are rarely implemented into the whole synthetic process for generating steroid intermediates. Novel steroid drug precursors and their idea...

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Detalles Bibliográficos
Autores principales: Yuan, Chen-Yang, Ma, Zhi-Guo, Zhang, Jing-Xian, Liu, Xiang-Cen, Du, Gui-Lin, Sun, Jun-Song, Shi, Ji-Ping, Zhang, Bao-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705162/
https://www.ncbi.nlm.nih.gov/pubmed/34949197
http://dx.doi.org/10.1186/s12934-021-01717-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705162/
https://www.ncbi.nlm.nih.gov/pubmed/34949197
http://dx.doi.org/10.1186/s12934-021-01717-w

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