Combined integrin α(v)β(3) and lactoferrin receptor targeted docetaxel liposomes enhance the brain targeting effect and anti-glioma effect

The integrin α(v)β(3) receptor and Lactoferrin receptor (LfR) are over-expressed in both cerebral microvascular endothelial cells and glioma cells. RGD tripeptide and Lf can specifically bind with integrin α(v)β(3) receptor and LfR, respectively. In our study, RGD and Lf dual-modified liposomes load...

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Detalles Bibliográficos
Autores principales: Qi, Na, Zhang, Shangqian, Zhou, Xiantai, Duan, Wenjuan, Gao, Duan, Feng, Jianfang, Li, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705194/
https://www.ncbi.nlm.nih.gov/pubmed/34949198
http://dx.doi.org/10.1186/s12951-021-01180-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705194/
https://www.ncbi.nlm.nih.gov/pubmed/34949198
http://dx.doi.org/10.1186/s12951-021-01180-0

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