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Combined integrin α(v)β(3) and lactoferrin receptor targeted docetaxel liposomes enhance the brain targeting effect and anti-glioma effect
The integrin α(v)β(3) receptor and Lactoferrin receptor (LfR) are over-expressed in both cerebral microvascular endothelial cells and glioma cells. RGD tripeptide and Lf can specifically bind with integrin α(v)β(3) receptor and LfR, respectively. In our study, RGD and Lf dual-modified liposomes load...
Autores principales: | Qi, Na, Zhang, Shangqian, Zhou, Xiantai, Duan, Wenjuan, Gao, Duan, Feng, Jianfang, Li, Aimin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705194/ https://www.ncbi.nlm.nih.gov/pubmed/34949198 http://dx.doi.org/10.1186/s12951-021-01180-0 |
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