Alterations in Kynurenine and NAD(+) Salvage Pathways during the Successful Treatment of Inflammatory Bowel Disease Suggest HCAR3 and NNMT as Potential Drug Targets

A meta-analysis of publicly available transcriptomic datasets was performed to identify metabolic pathways profoundly implicated in the progression and treatment of inflammatory bowel disease (IBD). The analysis revealed that genes involved in tryptophan (Trp) metabolism are upregulated in Crohn’s d...

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Detalles Bibliográficos
Autores principales: Wnorowski, Artur, Wnorowska, Sylwia, Kurzepa, Jacek, Parada-Turska, Jolanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705244/
https://www.ncbi.nlm.nih.gov/pubmed/34948292
http://dx.doi.org/10.3390/ijms222413497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705244/
https://www.ncbi.nlm.nih.gov/pubmed/34948292
http://dx.doi.org/10.3390/ijms222413497

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