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Ionic Regulation of T-Cell Function and Anti-Tumour Immunity

The capacity of T cells to identify and kill cancer cells has become a central pillar of immune-based cancer therapies. However, T cells are characterized by a dysfunctional state in most tumours. A major obstacle for proper T-cell function is the metabolic constraints posed by the tumour microenvir...

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Detalles Bibliográficos
Autores principales: Ginefra, Pierpaolo, Carrasco Hope, Helen, Spagna, Mattia, Zecchillo, Alessandra, Vannini, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705279/
https://www.ncbi.nlm.nih.gov/pubmed/34948472
http://dx.doi.org/10.3390/ijms222413668