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Characterizing the Interaction between the HTLV-1 Transactivator Tax-1 with Transcription Elongation Factor ELL2 and Its Impact on Viral Transactivation

The human T-cell leukemia virus type 1 (HTLV-1)-encoded transactivator and oncoprotein Tax-1 is essential for HTLV-1 replication. We recently found that Tax-1 interacts with transcription elongation factor for RNA polymerase II 2, ELL2, which enhances Tax-1-mediated transactivation of the HTLV-1 pro...

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Detalles Bibliográficos
Autores principales: Kohrt, Stephan, Strobel, Sarah, Mann, Melanie C., Sticht, Heinrich, Fleckenstein, Bernhard, Thoma-Kress, Andrea K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705299/
https://www.ncbi.nlm.nih.gov/pubmed/34948391
http://dx.doi.org/10.3390/ijms222413597