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MET Gene Dysregulation as a Promising Therapeutic Target in Lung Cancer—A Review

Several molecular abnormalities in the MET gene have been identified, including overexpression, amplification, point mutations, and “skipping mutation” in exon 14. Even though deregulated MET signaling occurs rarely in non-small cell lung cancer (NSCLC), it possesses tumorigenic activity. Since the...

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Detalles Bibliográficos
Autores principales: Terlecka, Paulina, Krawczyk, Paweł, Grenda, Anna, Milanowski, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705301/
https://www.ncbi.nlm.nih.gov/pubmed/34945842
http://dx.doi.org/10.3390/jpm11121370