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Novel Cysteine Protease Inhibitor Derived from the Haementeria vizottoi Leech: Recombinant Expression, Purification, and Characterization

Cathepsin L (CatL) is a lysosomal cysteine protease primarily involved in the terminal degradation of intracellular and endocytosed proteins. More specifically, in humans, CatL has been implicated in cancer progression and metastasis, as well as coronary artery diseases and others. Given this, the s...

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Detalles Bibliográficos
Autores principales: Linhares, Débora do Carmo, Faria, Fernanda, Kodama, Roberto Tadashi, Amorim, Adriane Michele Xavier Prado, Portaro, Fernanda Calheta Vieira, Trevisan-Silva, Dilza, Ferraz, Karla Fernanda, Chudzinski-Tavassi, Ana Marisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705320/
https://www.ncbi.nlm.nih.gov/pubmed/34941695
http://dx.doi.org/10.3390/toxins13120857