Theoretical Prediction and Explanation of Reaction Site Selectivity in the Addition of a Phenoxy Group to Perfluoropyrimidine, Perfluoropyridazine, and Perfluoropyrazine

Perfluoroaromatics, such as perfluoropyridine and perfluorobenzene, are privileged synthetic scaffolds in organofluorine methodology, undergoing a series of regioselective substitution reactions with a variety of nucleophiles. This unique chemical behavior allows for the synthesis of many perfluoroa...

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Detalles Bibliográficos
Autores principales: Fuhrer, Timothy J., Houck, Matthew, Chapman, Rachel M., Iacono, Scott T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705331/
https://www.ncbi.nlm.nih.gov/pubmed/34946720
http://dx.doi.org/10.3390/molecules26247637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705331/
https://www.ncbi.nlm.nih.gov/pubmed/34946720
http://dx.doi.org/10.3390/molecules26247637

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