Janerin Induces Cell Cycle Arrest at the G2/M Phase and Promotes Apoptosis Involving the MAPK Pathway in THP-1, Leukemic Cell Line

Janerin is a cytotoxic sesquiterpene lactone that has been isolated and characterized from different species of the Centaurea genus. In this study, janerin was isolated form Centaurothamnus maximus, and its cytotoxic molecular mechanism was studied in THP-1 human leukemic cells. Janerin inhibited th...

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Detalles Bibliográficos
Autores principales: Ahmed, Mohammad Z., Nasr, Fahd A., Qamar, Wajhul, Noman, Omar M., Khan, Javed Masood, Al-Mishari, Abdullah A., Alqahtani, Ali S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705386/
https://www.ncbi.nlm.nih.gov/pubmed/34946628
http://dx.doi.org/10.3390/molecules26247555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705386/
https://www.ncbi.nlm.nih.gov/pubmed/34946628
http://dx.doi.org/10.3390/molecules26247555

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