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Janerin Induces Cell Cycle Arrest at the G2/M Phase and Promotes Apoptosis Involving the MAPK Pathway in THP-1, Leukemic Cell Line
Janerin is a cytotoxic sesquiterpene lactone that has been isolated and characterized from different species of the Centaurea genus. In this study, janerin was isolated form Centaurothamnus maximus, and its cytotoxic molecular mechanism was studied in THP-1 human leukemic cells. Janerin inhibited th...
Autores principales: | Ahmed, Mohammad Z., Nasr, Fahd A., Qamar, Wajhul, Noman, Omar M., Khan, Javed Masood, Al-Mishari, Abdullah A., Alqahtani, Ali S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705386/ https://www.ncbi.nlm.nih.gov/pubmed/34946628 http://dx.doi.org/10.3390/molecules26247555 |
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