Acquired Drug Resistance Enhances Imidazoquinoline Efflux by P-Glycoprotein

Multidrug-Resistant (MDR) cancers attenuate chemotherapeutic efficacy through drug efflux, a process that transports drugs from within a cell to the extracellular space via ABC (ATP-Binding Cassette) transporters, including P-glycoprotein 1 (P-gp or ABCB1/MDR1). Conversely, Toll-Like Receptor (TLR)...

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Detalles Bibliográficos
Autores principales: Pulukuri, Anunay J., Burt, Anthony J., Opp, Larissa K., McDowell, Colin M., Davaritouchaee, Maryam, Nielsen, Amy E., Mancini, Rock J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705394/
https://www.ncbi.nlm.nih.gov/pubmed/34959691
http://dx.doi.org/10.3390/ph14121292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705394/
https://www.ncbi.nlm.nih.gov/pubmed/34959691
http://dx.doi.org/10.3390/ph14121292

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