HIV-1 Tat and Heparan Sulfate Proteoglycans Orchestrate the Setup of in Cis and in Trans Cell-Surface Interactions Functional to Lymphocyte Trans-Endothelial Migration

HIV-1 transactivating factor Tat is released by infected cells. Extracellular Tat homodimerizes and engages several receptors, including integrins, vascular endothelial growth factor receptor 2 (VEGFR2) and heparan sulfate proteoglycan (HSPG) syndecan-1 expressed on various cells. By means of experi...

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Detalles Bibliográficos
Autores principales: Urbinati, Chiara, Milanesi, Maria, Lauro, Nicola, Bertelli, Cinzia, David, Guido, D’Ursi, Pasqualina, Rusnati, Marco, Chiodelli, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705413/
https://www.ncbi.nlm.nih.gov/pubmed/34946571
http://dx.doi.org/10.3390/molecules26247488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705413/
https://www.ncbi.nlm.nih.gov/pubmed/34946571
http://dx.doi.org/10.3390/molecules26247488

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