Cargando…

Effects of Magnesium Orotate, Benfotiamine and a Combination of Vitamins on Mitochondrial and Cholinergic Function in the TgF344-AD Rat Model of Alzheimer’s Disease

Glucose hypometabolism, mitochondrial dysfunction, and cholinergic deficits have been reported in early stages of Alzheimer’s disease (AD). Here, we examine these parameters in TgF344-AD rats, an Alzheimer model that carries amyloid precursor protein and presenilin-1 mutations, and of wild type F344...

Descripción completa

Detalles Bibliográficos
Autores principales: Viel, Christian, Brandtner, Adrian T., Weißhaar, Alexander, Lehto, Alina, Fuchs, Marius, Klein, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705522/
https://www.ncbi.nlm.nih.gov/pubmed/34959619
http://dx.doi.org/10.3390/ph14121218