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Combining Human Genetics of Multiple Sclerosis with Oxidative Stress Phenotype for Drug Repositioning

In multiple sclerosis (MS), oxidative stress (OS) is implicated in the neurodegenerative processes that occur from the beginning of the disease. Unchecked OS initiates a vicious circle caused by its crosstalk with inflammation, leading to demyelination, axonal damage and neuronal loss. The failure o...

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Detalles Bibliográficos
Autores principales: Olla, Stefania, Steri, Maristella, Formato, Alessia, Whalen, Michael B., Corbisiero, Silvia, Agresti, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705550/
https://www.ncbi.nlm.nih.gov/pubmed/34959343
http://dx.doi.org/10.3390/pharmaceutics13122064