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Combining Human Genetics of Multiple Sclerosis with Oxidative Stress Phenotype for Drug Repositioning
In multiple sclerosis (MS), oxidative stress (OS) is implicated in the neurodegenerative processes that occur from the beginning of the disease. Unchecked OS initiates a vicious circle caused by its crosstalk with inflammation, leading to demyelination, axonal damage and neuronal loss. The failure o...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705550/ https://www.ncbi.nlm.nih.gov/pubmed/34959343 http://dx.doi.org/10.3390/pharmaceutics13122064 |