Current Progress in the Development of Hepatitis B Virus Capsid Assembly Modulators: Chemical Structure, Mode-of-Action and Efficacy

Hepatitis B virus (HBV) is a major causative agent of human hepatitis. Its viral genome comprises partially double-stranded DNA, which is complexed with viral polymerase within an icosahedral capsid consisting of a dimeric core protein. Here, we describe the effects of capsid assembly modulators (CA...

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Detalles Bibliográficos
Autores principales: Kim, Hyejin, Ko, Chunkyu, Lee, Joo-Youn, Kim, Meehyein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705634/
https://www.ncbi.nlm.nih.gov/pubmed/34946502
http://dx.doi.org/10.3390/molecules26247420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705634/
https://www.ncbi.nlm.nih.gov/pubmed/34946502
http://dx.doi.org/10.3390/molecules26247420

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