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Benzimidazole Derivatives as New and Selective Inhibitors of Arginase from Leishmania mexicana with Biological Activity against Promastigotes and Amastigotes

Leishmaniasis is a disease caused by parasites of the Leishmania genus that affects 98 countries worldwide, 2 million of new cases occur each year and more than 350 million people are at risk. The use of the actual treatments is limited due to toxicity concerns and the apparition of resistance strai...

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Detalles Bibliográficos
Autores principales: Betancourt-Conde, Irene, Avitia-Domínguez, Claudia, Hernández-Campos, Alicia, Castillo, Rafael, Yépez-Mulia, Lilián, Oria-Hernández, Jesús, Méndez, Sara T., Sierra-Campos, Erick, Valdez-Solana, Mónica, Martínez-Caballero, Siseth, Hermoso, Juan A., Romo-Mancillas, Antonio, Téllez-Valencia, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705706/
https://www.ncbi.nlm.nih.gov/pubmed/34948408
http://dx.doi.org/10.3390/ijms222413613