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Synergistic Interferon-Alpha-Based Combinations for Treatment of SARS-CoV-2 and Other Viral Infections

Background: There is an urgent need for new antivirals with powerful therapeutic potential and tolerable side effects. Methods: Here, we tested the antiviral properties of interferons (IFNs), alone and with other drugs in vitro. Results: While IFNs alone were insufficient to completely abolish repli...

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Detalles Bibliográficos
Autores principales: Ianevski, Aleksandr, Yao, Rouan, Zusinaite, Eva, Lello, Laura Sandra, Wang, Sainan, Jo, Eunji, Yang, Jaewon, Ravlo, Erlend, Wang, Wei, Lysvand, Hilde, Løseth, Kirsti, Oksenych, Valentyn, Tenson, Tanel, Windisch, Marc P., Poranen, Minna M., Nieminen, Anni I., Nordbø, Svein Arne, Fenstad, Mona Høysæter, Grødeland, Gunnveig, Aukrust, Pål, Trøseid, Marius, Kantele, Anu, Lastauskienė, Eglė, Vitkauskienė, Astra, Legrand, Nicolas, Merits, Andres, Bjørås, Magnar, Kainov, Denis E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705725/
https://www.ncbi.nlm.nih.gov/pubmed/34960758
http://dx.doi.org/10.3390/v13122489