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Generation of a Retargeted Oncolytic Herpes Virus Encoding Adenosine Deaminase for Tumor Adenosine Clearance

Background: Oncolytic viruses are immunotherapeutic agents that can be engineered to encode payloads of interest within the tumor microenvironment to enhance therapeutic efficacy. Their therapeutic potential could be limited by many avenues for immune evasion exerted by the tumor. One such is mediat...

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Detalles Bibliográficos
Autores principales: Gentile, Chiara, Finizio, Arianna, Froechlich, Guendalina, D’Alise, Anna Morena, Cotugno, Gabriella, Amiranda, Sara, Nicosia, Alfredo, Scarselli, Elisa, Zambrano, Nicola, Sasso, Emanuele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705735/
https://www.ncbi.nlm.nih.gov/pubmed/34948316
http://dx.doi.org/10.3390/ijms222413521