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Generation of a Retargeted Oncolytic Herpes Virus Encoding Adenosine Deaminase for Tumor Adenosine Clearance
Background: Oncolytic viruses are immunotherapeutic agents that can be engineered to encode payloads of interest within the tumor microenvironment to enhance therapeutic efficacy. Their therapeutic potential could be limited by many avenues for immune evasion exerted by the tumor. One such is mediat...
Autores principales: | Gentile, Chiara, Finizio, Arianna, Froechlich, Guendalina, D’Alise, Anna Morena, Cotugno, Gabriella, Amiranda, Sara, Nicosia, Alfredo, Scarselli, Elisa, Zambrano, Nicola, Sasso, Emanuele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705735/ https://www.ncbi.nlm.nih.gov/pubmed/34948316 http://dx.doi.org/10.3390/ijms222413521 |
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