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The Impact of Mutations on the Pathogenic and Antigenic Activity of SARS-CoV-2 during the First Wave of the COVID-19 Pandemic: A Comprehensive Immunoinformatics Analysis

An in-depth analysis of first-wave SARS-CoV-2 genome is required to identify various mutations that significantly affect viral fitness. In the present study, we performed a comprehensive in silico mutational analysis of 3C-like protease (3CLpro), RNA-dependent RNA polymerase (RdRp), and spike (S) pr...

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Detalles Bibliográficos
Autores principales: Baloch, Zulqarnain, Ikram, Aqsa, Hakim, Mohamad S., Awan, Faryal Mehwish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705738/
https://www.ncbi.nlm.nih.gov/pubmed/34960156
http://dx.doi.org/10.3390/vaccines9121410