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Human Stem Cell-Derived GABAergic Interneurons Establish Efferent Synapses onto Host Neurons in Rat Epileptic Hippocampus and Inhibit Spontaneous Recurrent Seizures
Epilepsy is a complex disorder affecting the central nervous system and is characterised by spontaneously recurring seizures (SRSs). Epileptic patients undergo symptomatic pharmacological treatments, however, in 30% of cases, they are ineffective, mostly in patients with temporal lobe epilepsy. Ther...
Autores principales: | Waloschková, Eliška, Gonzalez-Ramos, Ana, Mikroulis, Apostolos, Kudláček, Jan, Andersson, My, Ledri, Marco, Kokaia, Merab |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705828/ https://www.ncbi.nlm.nih.gov/pubmed/34948040 http://dx.doi.org/10.3390/ijms222413243 |
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