Honokiol Acts as a Potent Anti-Fibrotic Agent in the Liver through Inhibition of TGF-β1/SMAD Signaling and Autophagy in Hepatic Stellate Cells

Chronic liver injury may result in hepatic fibrosis, which can progress to cirrhosis and eventually liver failure. There are no drugs that are specifically approved for treating hepatic fibrosis. The natural product honokiol (HNK), a bioactive compound extracted from Magnolia grandiflora, represents...

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Detalles Bibliográficos
Autores principales: Kataoka, Seita, Umemura, Atsushi, Okuda, Keiichiro, Taketani, Hiroyoshi, Seko, Yuya, Nishikawa, Taichiro, Yamaguchi, Kanji, Moriguchi, Michihisa, Kanbara, Yoshihiro, Arbiser, Jack L., Shima, Toshihide, Okanoue, Takeshi, Itoh, Yoshito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705910/
https://www.ncbi.nlm.nih.gov/pubmed/34948151
http://dx.doi.org/10.3390/ijms222413354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705910/
https://www.ncbi.nlm.nih.gov/pubmed/34948151
http://dx.doi.org/10.3390/ijms222413354

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