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Fullerene Derivatives Prevent Packaging of Viral Genomic RNA into HIV-1 Particles by Binding Nucleocapsid Protein

Fullerene derivatives with hydrophilic substituents have been shown to exhibit a range of biological activities, including antiviral ones. For a long time, the anti-HIV activity of fullerene derivatives was believed to be due to their binding into the hydrophobic pocket of HIV-1 protease, thereby bl...

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Detalles Bibliográficos
Autores principales: Křížová, Ivana, Dostálková, Alžběta, Castro, Edison, Prchal, Jan, Hadravová, Romana, Kaufman, Filip, Hrabal, Richard, Ruml, Tomáš, Llano, Manuel, Echegoyen, Luis, Rumlová, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705927/
https://www.ncbi.nlm.nih.gov/pubmed/34960720
http://dx.doi.org/10.3390/v13122451