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Transcription Factor ChREBP Mediates High Glucose-Evoked Increase in HIF-1α Content in Epithelial Cells of Renal Proximal Tubules

Hyperglycemia/diabetes appears to be accompanied by the state of hypoxia, which especially affects kidneys. The aim of the study was to elucidate the mechanism of high glucose action on HIF-1α expression in renal proximal tubule epithelial cells. The research hypotheses included: (1) the participati...

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Detalles Bibliográficos
Autores principales: Owczarek, Aleksandra, Gieczewska, Katarzyna B., Jarzyna, Robert, Frydzinska, Zuzanna, Winiarska, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705933/
https://www.ncbi.nlm.nih.gov/pubmed/34948094
http://dx.doi.org/10.3390/ijms222413299