Cargando…
Transcription Factor ChREBP Mediates High Glucose-Evoked Increase in HIF-1α Content in Epithelial Cells of Renal Proximal Tubules
Hyperglycemia/diabetes appears to be accompanied by the state of hypoxia, which especially affects kidneys. The aim of the study was to elucidate the mechanism of high glucose action on HIF-1α expression in renal proximal tubule epithelial cells. The research hypotheses included: (1) the participati...
Autores principales: | Owczarek, Aleksandra, Gieczewska, Katarzyna B., Jarzyna, Robert, Frydzinska, Zuzanna, Winiarska, Katarzyna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705933/ https://www.ncbi.nlm.nih.gov/pubmed/34948094 http://dx.doi.org/10.3390/ijms222413299 |
Ejemplares similares
-
The structure of importin α and the nuclear localization peptide of ChREBP, and small compound inhibitors of ChREBP–importin α interactions
por: Jung, Hunmin, et al.
Publicado: (2020) -
Integrated Expression Profiling and Genome-Wide Analysis of ChREBP Targets Reveals the Dual Role for ChREBP in Glucose-Regulated Gene Expression
por: Jeong, Yun-Seung, et al.
Publicado: (2011) -
Islet ChREBP-β is increased in diabetes and controls ChREBP-α and glucose-induced gene expression via a negative feedback loop
por: Jing, Gu, et al.
Publicado: (2016) -
Carbohydrate Sensing Through the Transcription Factor ChREBP
por: Ortega-Prieto, Paula, et al.
Publicado: (2019) -
Melatonin Lowers HIF-1α Content in Human Proximal Tubular Cells (HK-2) Due to Preventing Its Deacetylation by Sirtuin 1
por: Owczarek, Aleksandra, et al.
Publicado: (2021)