The Stimulatory Effects of Intracellular α-Synuclein on Synaptic Transmission Are Attenuated by 2-Octahydroisoquinolin-2(1H)-ylethanamine

α-Synuclein (αSyn) species can be detected in synaptic boutons, where they play a crucial role in the pathogenesis of Parkinson’s Disease (PD). However, the effects of intracellular αSyn species on synaptic transmission have not been thoroughly studied. Here, using patch-clamp recordings in hippocam...

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Detalles Bibliográficos
Autores principales: Ramirez, Alejandra E., Fernández-Pérez, Eduardo J., Olivos, Nicol, Burgos, Carlos F., Boopathi, Subramanian, Armijo-Weingart, Lorena, Pacheco, Carla R., González, Wendy, Aguayo, Luis G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705949/
https://www.ncbi.nlm.nih.gov/pubmed/34948050
http://dx.doi.org/10.3390/ijms222413253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705949/
https://www.ncbi.nlm.nih.gov/pubmed/34948050
http://dx.doi.org/10.3390/ijms222413253

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