Cargando…

X-ray Characterization of Conformational Changes of Human Apo- and Holo-Transferrin

Human serum transferrin (Tf) is a bilobed glycoprotein whose function is to transport iron through receptor-mediated endocytosis. The mechanism for iron release is pH-dependent and involves conformational changes in the protein, thus making it an attractive system for possible biomedical application...

Descripción completa

Detalles Bibliográficos
Autores principales: Campos-Escamilla, Camila, Siliqi, Dritan, Gonzalez-Ramirez, Luis A., Lopez-Sanchez, Carmen, Gavira, Jose Antonio, Moreno, Abel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705962/
https://www.ncbi.nlm.nih.gov/pubmed/34948188
http://dx.doi.org/10.3390/ijms222413392