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X-ray Characterization of Conformational Changes of Human Apo- and Holo-Transferrin
Human serum transferrin (Tf) is a bilobed glycoprotein whose function is to transport iron through receptor-mediated endocytosis. The mechanism for iron release is pH-dependent and involves conformational changes in the protein, thus making it an attractive system for possible biomedical application...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705962/ https://www.ncbi.nlm.nih.gov/pubmed/34948188 http://dx.doi.org/10.3390/ijms222413392 |