Metformin Treatment Attenuates Brain Inflammation and Rescues PACAP/VIP Neuropeptide Alterations in Mice Fed a High-Fat Diet

High-fat diet (HFD)-induced comorbid cognitive and behavioural impairments are thought to be the result of persistent low-grade neuroinflammation. Metformin, a first-line medication for the treatment of type-2 diabetes, seems to ameliorate these comorbidities, but the underlying mechanism(s) are not...

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Detalles Bibliográficos
Autores principales: Mandwie, Mawj, Karunia, Jocelyn, Niaz, Aram, Keay, Kevin A., Musumeci, Giuseppe, Rennie, Claire, McGrath, Kristine, Al-Badri, Ghaith, Castorina, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706124/
https://www.ncbi.nlm.nih.gov/pubmed/34948457
http://dx.doi.org/10.3390/ijms222413660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706124/
https://www.ncbi.nlm.nih.gov/pubmed/34948457
http://dx.doi.org/10.3390/ijms222413660

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