Ionophore Ability of Carnosine and Its Trehalose Conjugate Assists Copper Signal in Triggering Brain-Derived Neurotrophic Factor and Vascular Endothelial Growth Factor Activation In Vitro

l-carnosine (β-alanyl-l-histidine) (Car hereafter) is a natural dipeptide widely distributed in mammalian tissues and reaching high concentrations (0.7–2.0 mM) in the brain. The molecular features of the dipeptide underlie the antioxidant, anti-aggregating and metal chelating ability showed in a lar...

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Detalles Bibliográficos
Autores principales: Naletova, Irina, Greco, Valentina, Sciuto, Sebastiano, Attanasio, Francesco, Rizzarelli, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706131/
https://www.ncbi.nlm.nih.gov/pubmed/34948299
http://dx.doi.org/10.3390/ijms222413504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706131/
https://www.ncbi.nlm.nih.gov/pubmed/34948299
http://dx.doi.org/10.3390/ijms222413504

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