A Listeria monocytogenes-Based Vaccine Formulation Reduces Vertical Transmission and Leads to Enhanced Pup Survival in a Pregnant Neosporosis Mouse Model

The apicomplexan parasite Neospora caninum is the worldwide leading cause of abortion and stillbirth in cattle. An attenuated mutant Listeria monocytogenes strain (Lm3Dx) was engineered by deleting the virulence genes actA, inlA, and inlB in order to avoid systemic infection and to target the vector...

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Detalles Bibliográficos
Autores principales: Imhof, Dennis, Pownall, William Robert, Monney, Camille, Oevermann, Anna, Hemphill, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706174/
https://www.ncbi.nlm.nih.gov/pubmed/34960146
http://dx.doi.org/10.3390/vaccines9121400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706174/
https://www.ncbi.nlm.nih.gov/pubmed/34960146
http://dx.doi.org/10.3390/vaccines9121400

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