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Echinocandin Drugs Induce Differential Effects in Cytokinesis Progression and Cell Integrity

Fission yeast contains three essential β(1,3)-D-glucan synthases (GSs), Bgs1, Bgs3, and Bgs4, with non-overlapping roles in cell integrity and morphogenesis. Only the bgs4(+) mutants pbr1-8 and pbr1-6 exhibit resistance to GS inhibitors, even in the presence of the wild-type (WT) sequences of bgs1(+...

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Detalles Bibliográficos
Autores principales: Yagüe, Natalia, Gómez-Delgado, Laura, Curto, M. Ángeles, Carvalho, Vanessa S. D., Moreno, M. Belén, Pérez, Pilar, Ribas, Juan Carlos, Cortés, Juan Carlos G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706178/
https://www.ncbi.nlm.nih.gov/pubmed/34959732
http://dx.doi.org/10.3390/ph14121332