Inclusion of the Guinea Pig Cytomegalovirus Pentameric Complex in a Live Virus Vaccine Aids Efficacy against Congenital Infection but Is Not Essential for Improving Maternal and Neonatal Outcomes

The development of a vaccine against congenital human cytomegalovirus (HCMV) infection is a major priority. The pentameric complex (PC) of virion envelope proteins gH, gL, UL128, UL130, and UL131A is a key vaccine target. To determine the importance of immunity to the homologous PC encoded by guinea...

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Detalles Bibliográficos
Autores principales: Schleiss, Mark R., Fernández-Alarcón, Claudia, Hernandez-Alvarado, Nelmary, Wang, Jian Ben, Geballe, Adam P., McVoy, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706200/
https://www.ncbi.nlm.nih.gov/pubmed/34960639
http://dx.doi.org/10.3390/v13122370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706200/
https://www.ncbi.nlm.nih.gov/pubmed/34960639
http://dx.doi.org/10.3390/v13122370

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