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Inclusion of the Guinea Pig Cytomegalovirus Pentameric Complex in a Live Virus Vaccine Aids Efficacy against Congenital Infection but Is Not Essential for Improving Maternal and Neonatal Outcomes

The development of a vaccine against congenital human cytomegalovirus (HCMV) infection is a major priority. The pentameric complex (PC) of virion envelope proteins gH, gL, UL128, UL130, and UL131A is a key vaccine target. To determine the importance of immunity to the homologous PC encoded by guinea...

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Detalles Bibliográficos
Autores principales:	Schleiss, Mark R., Fernández-Alarcón, Claudia, Hernandez-Alvarado, Nelmary, Wang, Jian Ben, Geballe, Adam P., McVoy, Michael A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706200/ https://www.ncbi.nlm.nih.gov/pubmed/34960639 http://dx.doi.org/10.3390/v13122370

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