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Restraint upon Embryonic Metatarsal Ex Vivo Growth by Hydrogel Reveals Interaction between Quasi-Static Load and the mTOR Pathway

Mechanical cues play a vital role in limb skeletal development, yet their influence and underpinning mechanisms in the regulation of endochondral ossification (EO) processes are incompletely defined. Furthermore, interactions between endochondral growth and mechanics and the mTOR/NF-ĸB pathways are...

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Detalles Bibliográficos
Autores principales: Caetano-Silva, Soraia, Simbi, Bigboy H., Marr, Neil, Hibbert, Andrew, Allen, Steve P., Pitsillides, Andrew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706285/
https://www.ncbi.nlm.nih.gov/pubmed/34948015
http://dx.doi.org/10.3390/ijms222413220