Measuring Proviral HIV-1 DNA: Hurdles and Improvements to an Assay Monitoring Integration Events Utilising Human Alu Repeat Sequences

Integrated HIV-1 DNA persists despite antiretroviral therapy and can fuel viral rebound following treatment interruption. Hence, methods to specifically measure the integrated HIV-1 DNA portion only are important to monitor the reservoir in eradication trials. Here, we provide an up-to-date overview...

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Detalles Bibliográficos
Autores principales: Malatinkova, Eva, Thomas, Jordan, De Spiegelaere, Ward, Rutsaert, Sofie, Geretti, Anna Maria, Pollakis, Georgios, Paxton, William A., Vandekerckhove, Linos, Ruggiero, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706387/
https://www.ncbi.nlm.nih.gov/pubmed/34947941
http://dx.doi.org/10.3390/life11121410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706387/
https://www.ncbi.nlm.nih.gov/pubmed/34947941
http://dx.doi.org/10.3390/life11121410

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